Reno-invasive fungal infection presenting as acute renal failure: Importance of renal biopsy for early diagnosis.

Reno-invasive fungal infection presenting as acute renal failure: Importance of renal biopsy for early diagnosis. Saudi J Kidney Dis Transpl. 2014 Nov-Dec;25(6):1282-4 Authors: Ranjan P, Chipde SS, Vashistha S, Kumari N, Kapoor R Abstract Renal zygomycosis, caused by invasive fungi, is a rare and potentially fatal infec-tion. The patient usually presents with non-specific symptoms and renal failure. A 34-year-old male non-diabetic and without any predisposing factors for systemic fungal infection presented to the emergency department with diffuse abdominal pain, high-grade fever and acute renal failure with a serum creatinine of 6.5. A computed tomography showed bilateral diffuse globular nephromegaly. A urine smear for fungal examination showed right angle branching hyphae and kidney biopsy showed fungal hyphae within the glomeruli, tubules and interstitium. Although radiological investigations can give us a clue, the definitive diagnosis can only be made by kidney biopsy. A high index of suspicion and timely diagnosis is important for a proper management. PMID: 25394451 [PubMed - in process]
Source: Saudi Journal of Kidney Diseases and Transplantation - Category: Urology & Nephrology Authors: Tags: Saudi J Kidney Dis Transpl Source Type: research