Biodistribution, pharmacokinetics and radioimmunotherapy of 188 Re-cetuximab in NCI-H292 human lung tumor-bearing nude mice

Conclusion The tumor targeting and localization of 188Re-cetuximab were confirmed in this study. Synergistic therapeutic efficacy was demonstrated for the radioimmunotherapy of188Re-cetuximab. The results of this study reveal the potential advantage and benefit obtained from188Re-cetuximab for diagnosis and therapy of oncology applications in the future.

Source: Investigational New Drugs - January 5, 2019 Category: Drugs & Pharmacology Source Type: research