316. I-123 based pre-therapy dosimetry for I-131 thyroid cancer therapy in paediatric patient

The use of I-123-NaI has several possible advantages for pre-therapeutic red marrow (RM) dosimetry in I-131 differentiated thyroid cancer (DTC) therapy: it reduces radiation exposure and provides high-sensitivity diagnostic scans in paediatric patients. Unfortunately, the short physical half-time of I-123 could be inadequate for dosimetric accuracy. The aim of this study was to investigate the possibility of using I-123 for pre-therapeutic RM dosimetry of DTC paediatric patients comparing whole-body (WB) and blood residence time ( τ) calculated during pre-treatment (PT) and in-treatment (IT) dosimetry.
Source: Physica Medica: European Journal of Medical Physics - Category: General Medicine Authors: Source Type: research