Genetics of Human Primary Hypertension: Focus on Hormonal Mechanisms.

In conclusion: primary hypertension is a syndrome; many proposed genes are likely to be false positives; deep phenotyping will be required to determine the utility of genetics in the treatment of hypertension. Yet, to date, the positive genes are associated with nearly 50% of primary hypertensives, suggesting that in the near term precise, mechanistically driven treatment and prevention strategies for the specific primary hypertension sub-groups are feasible. PMID: 30590482 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30590482?dopt=Abstract

Source: ENDOCR REV - December 24, 2018 Category: Endocrinology Authors: Manosroi W, Williams GH Tags: Endocr Rev Source Type: research