Overexpression of MicroRNA-1 in Prostate Cancer Cells Modulates the Blood Vessel System of an In Vivo Hen's Egg Test-Chorioallantoic Membrane Model

Conclusion: MiR-1 had a tumor-suppressive and anti-angiogenic effect in an in vivo PC model. In the clinic, miR-1-mediated anti-angiogenesis would result in reduced tumor supply and increased hypoxic stress inside the tumor. Thus, miR-1 restoration by nucleic acid-based miR-1 mimetics would represent a promising option for future PC therapy.

http://iv.iiarjournals.org/cgi/content/short/33/1/41?rss=1

Source: In Vivo - December 26, 2018 Category: Research Authors: REUTER, A., SCKELL, A., BRANDENBURG, L.-O., BURCHARDT, M., KRAMER, A., STOPE, M. B. Tags: Experimental Studies Source Type: research