E4BP4 is a repressor of epigenetically regulated SOSTDC1 expression in breast cancer cells

Conclusion From our results we conclude that the transcriptional repressor E4BP4 plays a role in repressing epigenetically regulated SOSTDC1 expression in breast cancer cells, which can be reverted by E4BP4 silencing.

http://link.springer.com/10.1007/s13402-014-0204-6

Source: Cellular Oncology - October 22, 2014 Category: Cancer & Oncology Source Type: research