Genetic variants of glutathione S-transferase and the risk of acute myeloid leukemia in a Saudi population

ConclusionIn conclusion, there was no statistical association of the genotypes and alleles in GSTM1, GSTT1, and GSTP1 with AML. Our results confirm the negative association of the investigated genetic markers with susceptibility to AML. Further association studies would be required in different ethnic populations to facilitate a meta-analysis in the future. Our findings suggest that the GST gene has no role in the pathogenesis of AML in patients from Saudi Arabia.
Source: Saudi Journal of Biological Sciences - Category: Biology Source Type: research