An increase in intracellular p62/NBR1 and persistence of Burkholderia mallei and B. pseudomallei in infected mice linked to autophagy deficiency
ConclusionTaken together, our results suggest that an increase in intracellular p62/NBR1 may be a potential host cell biomarker ofB. mallei orB. pseudomallei infections, and identifying autophagy manipulation may potentially aid to therapeutic approach for complete clearance of the pathogen.
Source: Immunity, Inflammation and Disease - Category: Allergy & Immunology Authors: Kamal U. Saikh,
Jennifer L. Dankmeyer,
Xiankun Zeng,
Robert G. Ulrich,
Kei Amemiya Tags: ORIGINAL RESEARCH Source Type: research
More News: Allergy & Immunology | Burkholderia | Burkholderia Mallei | Endemics | Glanders | Liver | Study | Urology & Nephrology