Morbidity pattern and interferon gamma level in sickle cell anemia patients with autosplenectomy

Conclusion: This study showed a higher prevalence of infection and bone pain crisis among SCA patients with autosplenectomy than in SCA patients without autosplenectomy. It also showed comparable level of IFN-γ in the 2 groups of patients. Patients with autosplenectomy may benefit from early institution of drugs such as hydroxyurea to improve quality of life.

Source: Nigerian Journal of Clinical Practice - December 18, 2018 Category: Rural Health Authors: CI Okongwu FA Fasola AJ Adekanmi AA Onifade Source Type: research