Genome-wide RNAseq study of the molecular mechanisms underlying microglia activation in response to pathological tau perturbation in the rTg4510 tau transgenic animal model

Activation of microglia, the resident immune cells of the central nervous system, is a prominent pathological hallmark of Alzheimer ’s disease (AD). However, the gene expression changes underlying microglia act...

Source: Molecular Neurodegeneration - December 17, 2018 Category: Neurology Authors: Hong Wang, Yupeng Li, John W. Ryder, Justin T. Hole, Philip J. Ebert, David C. Airey, Hui-Rong Qian, Benjamin Logsdon, Alice Fisher, Zeshan Ahmed, Tracey K. Murray, Annalisa Cavallini, Suchira Bose, Brian J. Eastwood, David A. Collier, Jeffrey L. Dage & h Tags: Research article Source Type: research