Prevalence of Germline Mutations in Polyposis and Colorectal Cancer-associated Genes in Patients With Multiple Colorectal Polyps

Guidelines recommend genetic testing of patients with 10 or more cumulative adenomatous polyps. However, little is known about the utility of these tests —especially for older patients. We aimed to determine the prevalence of pathogenic mutations in patients with multiple colorectal polyps, stratified by age.

Source: Clinical Gastroenterology and Hepatology - December 14, 2018 Category: Gastroenterology Authors: Peter P. Stanich, Rachel Pearlman, Alice Hinton, Stephanie Gutierrez, Holly LaDuca, Heather Hampel, Kory Jasperson Source Type: research