Study on Biological Characteristics and Mechanism of Paclitaxel Induced Drug Resistance in Endometrial Carcinoma Cells.

Conclusion: Paclitaxel can inhibit Ishikawa and Ishikawa-TAX cell via PI3K/Akt/mTOR signaling pathway. Paclitaxel and NVP-BEZ235 cotreatment can enhance the inhibitory effect. PMID: 30175145 [PubMed - indexed for MEDLINE]

https://www.ncbi.nlm.nih.gov/pubmed/30175145?dopt=Abstract

Source: Biomed Res - December 14, 2018 Category: Research Authors: Ding J, Li M, Deng L, Li T Tags: Biomed Res Int Source Type: research