Increasing lean muscle mass in mice via nanoparticle-mediated hepatic delivery of follistatin mRNA

Conclusion: Based on the obtained results demonstrating an increased muscle mass as well as restricted fat accumulation, this nanoplatform might be a milestone in the development of mRNA technologies and the treatment of muscle wasting disorders.

Source: Theranostics - December 7, 2018 Category: Molecular Biology Authors: Canan Schumann, Duc X. Nguyen, Mason Norgard, Yulia Bortnyak, Tetiana Korzun, Stephanie Chan, Anna St. Lorenz, Abraham S. Moses, Hassan A. Albarqi, Leon Wong, Katherine Michaelis, Xinxia Zhu, Adam W. G. Alani, Olena R. Taratula, Stephanie Krasnow, Daniel Tags: Research Paper Source Type: research