Alkaline Phosphatase Controls Lineage Switching of Mesenchymal Stem Cells by Regulating the LRP6/GSK3 β Complex in Hypophosphatasia

Conclusion: Based on our findings, TNSALP acts as a signal regulator to control lineage switching of BMMSCs by regulating the LRP6/GSK3β cascade.

Source: Theranostics - December 7, 2018 Category: Molecular Biology Authors: Wenjia Liu, Liqiang Zhang, Kun Xuan, Chenghu Hu, Liya Li, Yongjie Zhang, Fang Jin, Yan Jin Tags: Research Paper Source Type: research