The role of Chamaejasmine in cellular apoptosis and autophagy in MG-63 cells.

Conclusion：Our results show that chamaejasmine promotes apoptosis and autophagy by activating AMPK /mTOR signaling pathways with involvement of ROS in MG-63 cells. Chamaejasmine is a promising anti-cancer agent in OS treatment and further studies are needed to confirm its efficacy and safety in vivo or other cancer cells.
PMID: 30463909 [PubMed - as supplied by publisher]

Source: Bioscience Reports - November 21, 2018 Category: Biomedical Science Authors: Yang D, Zhang H, Wu J, Ma R, Li Z, Wang K, Yang F Tags: Biosci Rep Source Type: research