Inter- and Intra-Rater Reliability of Computer-Assisted Planimetry in Experimental Stroke Research

ConclusionComputer-assisted planimetry can be an appropriate method to determine hemispheric or ischemic lesion volume in rodents but requires a sufficiently long learning period of approximately two months. Even an experienced investigator can generate data with serious variation. Inter- and intra-rater-dependent bias should be considered during the design and performance of respective studies.
Source: Journal of Neuroscience Methods - Category: Neuroscience Source Type: research