Therapy ‐related acute myeloid leukemia after chemotherapy in extensive disease‐small cell lung cancer

We experienced therapy ‐related acute myeloid leukemia (t‐AML) in a patient with extensive disease‐small cell lung cancer (ED‐SCLC). This case is rare and has educational message because ED‐SCLC has a poor prognosis and often cannot survive until developing therapy related hematological malignancy. Furthermore t his case had unique chromosomal abnormalities. With recent advances in chemotherapy and radiotherapy, the prognosis of lung cancer has improved, while t‐AML has been increasing in frequency. Key Clinical MessageWe experienced therapy ‐related acute myeloid leukemia (t‐AML) in a patient with extensive disease‐small cell lung cancer (ED‐SCLC). This case is rare and has educational message because ED‐SCLC has a poor prognosis and often cannot survive until developing therapy related hematological malignancy. Furthermore t his case had unique chromosomal abnormalities. With recent advances in chemotherapy and radiotherapy, the prognosis of lung cancer has improved, while t‐AML has been increasing in frequency.

Source: Clinical Case Reports - November 19, 2018 Category: General Medicine Authors: Naoko Ueda, Kohei Fujita, Yoshiaki Okuno, Koichi Nakatani, Tadashi Mio Tags: CASE REPORT Source Type: research