Goodbye'Gluten-Free'? Celiac Disease Vaccine May Make It Possible

WEDNESDAY, Nov. 14, 2018 -- People with celiac disease must follow a very restrictive diet, but an experimental vaccine may offer many of them the freedom to eat more normally. Celiac disease is an autoimmune disorder. If someone with the disease...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news

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AbstractDefective spleen function increases susceptibility to bacterial infections which can be prevented by vaccine prophylaxis. Splenic hypofunction can be found in a number of autoimmune disorders; however, no data are available regarding autoimmune atrophic gastritis (AAG), autoimmune enteropathy (AIE) and autoimmune liver disease (AILD). Peripheral blood samples from patients with AAG (n = 40), AIE (n = 3) and AILD (n = 40) were collected. Patients affected by autoimmune disorders already known to be associated with splenic hypofunction, i.e. coeliac disease (CD) and ulcerativ...
Source: Internal and Emergency Medicine - Category: Emergency Medicine Source Type: research
In the United States and other developed countries, we have seen a shift over the past several decades in the types of illness people struggle with. Public health campaigns around vaccination, sanitation, and judicious use of antibiotics have largely eradicated many infectious illnesses. As the nature of disease has shifted to inflammatory conditions, we’ve seen a striking increase in allergy and autoimmune conditions such as diabetes, obesity, inflammatory bowel disease, celiac disease, and multiple sclerosis. The microbiome — the varied and teeming colonies of gut bacteria inside of us — may be helping ...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Digestive Disorders Family Planning and Pregnancy Inflammation Probiotics Source Type: blogs
Conclusions: RV vaccination using RotaTeq did not alter the occurrence of DM1 but decreased the prevalence of CD in childhood and adolescence. We propose that wild-type RV may trigger CD and the triggering effect can be prevented or reduced by RV vaccination.
Source: The Pediatric Infectious Disease Journal - Category: Infectious Diseases Tags: Vaccine Reports Source Type: research
CONCLUSION: A positive association with influenza diagnosis is consistent with the hypothesis that infections may play a role in CD development. We could neither confirm a causal association with pandemic vaccination, nor refute entirely a small excess risk. PMID: 29076383 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Gastroenterology - Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research
ConclusionUnmasking of conditions at vaccination visits is a plausible explanation for the increased risk associated with qHPV in this study because coeliac disease is underdiagnosed in Scandinavian populations. In conclusion, our study of serious adverse event rates in qHPV‐vaccinated and qHPV‐unvaccinated adult women 18–44 years of age did not raise any safety issues of concern.
Source: Journal of Internal Medicine - Category: Internal Medicine Authors: Tags: Original Article Source Type: research
We read with a great interest the recent article by Mormile R, speculating that a blunted antibody response to HBV vaccine might be a potential predictor of autoimmunity during lifetime. Several studies described a reduced antibody protection provided by HBV vaccine in children affected with different autoimmune diseases, including type I diabetes mellitus, celiac disease and idiopathic juvenile arthritis.[1] However, the immune-pathological relationship is supposed to be quite complex and it is still impossible to distinguish between the cause and the effect.
Source: Medical Hypotheses - Category: Biomedical Science Authors: Source Type: research
AbstractThis review reports main progresses in various pediatric issues published in Italian Journal of Pediatrics and in international journals in 2016. New insights in clinical features or complications of several disorders may be useful for our better understanding. They comprise severe asthma, changing features of lupus erythematosus from birth to adolescence, celiac disease, functional gastrointestinal disorders, Moebius syndrome, recurrent pneumonia. Risk factors for congenital heart defects, Kawasaki disease have been widely investigated. New diagnostic tools are available for ascertaining brucellosis, celiac diseas...
Source: Italian Journal of Pediatrics - Category: Pediatrics Source Type: research
Conclusion The US has the highest vaccination rate of all industrialized countries. US children are experiencing a health epidemic with more chronic diseases than ever before in our history. The US has the highest infant mortality in a study comparing America with 29 other developed countries. Children in the US suffered with more autism than in all other countries studied. Studies comparing vaccinated and unvaccinated show conclusively that unvaccinated children enjoy far superior health. Research and data demonstrate that vaccines cause neurological damage and contribute to significant health damage. Vaccines are a major...
Source: vactruth.com - Category: Allergy & Immunology Authors: Tags: Logical Michelle Goldstein Recent Articles Top Picks autism truth about vaccines vaccine injuries Source Type: blogs
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Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
Abstract Proline‐ and glutamine‐rich gluten proteins are one of the major constituents of cereal dietary proteins, which are largely resistant to complete cleavage by the human gastrointestinal (GI) digestive enzymes. Partial digestion of gluten generates approximately 35 amino acids (aa) immunomodulatory peptides which activate T‐cell–mediated immune system, followed by immunological inflammation of mucosa leading to the onset of celiac disease (CD). CD is an autoimmune disease associated with HLA–DQ2/DQ8 polymorphism and dysbiosis of gut microbiota. CD is either diagnosed using duodenal mucosal biopsis ...
Source: Journal of Food Science - Category: Food Science Authors: Tags: Concise Reviews & Hypotheses in Food Science Source Type: research
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