Coverage and timeliness of vaccination and the validity of routine estimates: Insights from a vaccine registry in Kenya.

CONCLUSIONS: Standard coverage surveys in 12-23 month old children overestimate protection by ignoring timeliness, and survivor and recall biases. Where delayed vaccination is common, up-to-date coverage will give biased estimates of population immunity. Surveys and administrative methods also underestimate FIC prevalence. Better measurement of coverage and more sophisticated analyses are required to control vaccine preventable diseases. PMID: 30416017 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30416017?dopt=Abstract

Source: Vaccine - November 8, 2018 Category: Allergy & Immunology Authors: Adetifa IMO, Karia B, Mutuku A, Bwanaali T, Makumi A, Wafula J, Chome M, Mwatsuma P, Bauni E, Hammitt LL, Mataza C, Tabu C, Kamau T, Williams TN, Scott JAG Tags: Vaccine Source Type: research