Septal Alcohol Ablation Versus Myectomy for Symptomatic Hypertrophic Obstructive Cardiomyopathy: Systematic Review and Meta ‐analysis

BackgroundSurgical myectomy (SM) and Alcohol septal ablation (ASA) are effective therapies for patients with hypertrophic cardiomyopathy who remain symptomatic despite medical therapy. A plethora of data has recently emerged on the long ‐term outcomes of these procedures. We hence sought to perform an updated meta‐analysis comparing both procedures.MethodsStudies reporting long ‐term (>3 ‐years) outcomes of SM and/or ASA were included. The primary endpoint was all‐cause mortality. Secondary endpoints included cardiovascular mortality, sudden cardiac death (SCD), reintervention and complications including death, pacemaker implantation and stroke.Results22 ASA cohorts (n=4,213; follow ‐up=6.6‐years) and 23 SM cohorts (n=4,240; follow‐up=6.8‐years) were included. Septal myectomy was associated with higher periprocedural mortality and stroke (2% vs. 1.2%, p=0.009 and 1.5% vs. 0.8% p=0.013, respectively), but ASA was associated with more need of pacemaker (10% vs. 5%, p
Source: Clinical Cardiology - Category: Cardiology Authors: Tags: REVIEW Source Type: research

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The objective of this study was to develop a simple method for detecting lipid oxidation through the color change of a composite film. Schiff's reagent which can form color compound with lipid oxidation products—aldehydes was incorporated into polyvinyl alcohol (PVA) to form the composite film. The effects of PVA molecular weight (Mw), Schiff's reagent/PVA ratio and glycerol content on the response of the composite film to aldehyde were investigated. Sunflower seed oil with various extent of oxidation was used to evaluate the effectiveness of the composite film for lipid oxidation detection. The results showed that t...
Source: LWT Food Science and Technology - Category: Food Science Source Type: research
CONCLUSIONS: Increased IP is found in 23% of cirrhotic patients. Permeability alterations are significantly more pronounced in patients with advanced LC with the presence of ascites and in those with alcoholic etiology. PMID: 31957845 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Publication date: Available online 20 January 2020Source: Reactive and Functional PolymersAuthor(s): Yongli Zhang, Jing Tang, Keke Feng, Huilin Zhao, Weiwei Yan, Zhiming Sun, Fuming Wu, Yu Sun, Jianping GaoAbstractInverse opal hydrogel films composed of hydroxyethyl 2-methacrylate and phenylboronic acid (IOHGHEMA+3APBA) were prepared by a convenient ultrasonic-induced self-assembly method. The IOHGHEMA+3APBA films had brilliant blue-violet color when they were immersed in deionized water and reached swelling equilibrium. The IOHGHEMA+3APBA films were used as sensors to detect chemicals with similar structures. When the IOH...
Source: Reactive and Functional Polymers - Category: Chemistry Source Type: research
Publication date: Available online 20 January 2020Source: Chinese Chemical LettersAuthor(s): Xiao Zhang, Yaohua Xu, Hao Liu, Wenrui Zhao, Anjie Ming, Feng WeiAbstractA homogeneous porous Co3O4-ZnO nanomaterial (Zn-CoOx) was successfully fabricated by precipitation-annealing route. The as-prepared Zn-CoOx exhibited good response, reliable reversibility and good selectivity towards alcohols, which attributed to the porous structure and p-n heterojunction formed between Co3O4 and ZnO. In particular, the different Fermi levels of Co3O4 and ZnO leaded to a further increase the depth of the space charge layer, which improved the...
Source: Chinese Chemical Letters - Category: Chemistry Source Type: research
Publication date: Available online 21 January 2020Source: Chemical Engineering JournalAuthor(s): Shujuan Zhang, Qiantao Shi, George Korfiatis, Christos Christodoulatos, Hongjun Wang, Xiaoguang MengAbstractChromium (Cr(VI)) is one of the most toxic heavy metals threatening humans’ health and the environment. Water-stable poly(vinyl alcohol)/polyethylenimine (PVA/PEI) nanofibers were fabricated through electrospinning and evaluated for Cr(VI) removal from water in batch experiments. The adsorption behavior and removal mechanisms of Cr(VI) by PVA/PEI nanofibers were systematically investigated through a combination of b...
Source: Chemical Engineering Journal - Category: Chemistry Source Type: research
Publication date: Available online 20 January 2020Source: Chemical Engineering and Processing - Process IntensificationAuthor(s): Patrick V. MangiliAbstractThis paper deals with the design of two new, intensified pressure-swing flowsheets for the separation of di-n-propyl ether and n-propanol based on direct heat integration and vapor recompression. Such alternatives are then compared with the conventional scheme regarding thermoeconomic performance and environmental impacts. The thermodynamic evaluation was based on the processes’ energy consumptions, exergetic efficiencies and exergy intensities. The economic analy...
Source: Chemical Engineering and Processing: Process Intensification - Category: Chemistry Source Type: research
Sea eagles in England | Loneliness and churches | Circumcision and Shakespeare | English usage | Sperm donationsSo a sea eagle has chosen to live in Oxfordshire (Report, 18 January). It is not the first time. Archaeologists digging near Oxford have discovered sea eagle bones on bronze age and Anglo-Saxon sites. And the name of the village Earley, on the Thames near Reading, means “eagle wood” – probably because of the presence there of sea eagles’ nests over 1,000 years ago. Let’s hope this magnificent bird finds a mate and stays around.David MilesRetiredchiefarchaeologist, English Heritage&bu...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Birds Animals Wildlife Environment Archaeology Science Loneliness Society Circumcision Health & wellbeing Linguistics Education Alcohol Reproduction Biology Reproductive rights Source Type: news
BACKGROUND: Evidence demonstrates that seeing alcoholic beverages in electronic media increases alcohol initiation and frequent and excessive drinking, particularly among young people. To efficiently assess this exposure, the aim was to develop the Alcohol...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
We examined correspondence between baseline trait-level and daily brief measures of alcohol demand, and whether demand chan...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
BACKGROUND: The present study aims to (i) identify patterns in the changes of endorsed positive alcohol expectancies (AEs) through early adolescence and (ii) examine associated childhood social context predictors of such profiles. METHODS: We used ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
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