The effectiveness of 4DCT in children and adults: A pooled analysis.

CONCLUSIONS: Overall variability is smaller in children than in adults, indicating that respiratory motion is more regular in children than in adults. This implies that a single pretreatment 4DCT could be a good representation of daily respiratory motion in children and will be at least equally beneficial for planning purposes as it is in adults. PMID: 30414252 [PubMed - as supplied by publisher]
Source: Journal of Applied Clinical Medical Physics - Category: Physics Authors: Tags: J Appl Clin Med Phys Source Type: research

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Publication date: Available online 14 September 2019Source: European Journal of RadiologyAuthor(s): Christophe T. Arendt, Rouben Czwikla, Lukas Lenga, Julian L. Wichmann, Moritz H. Albrecht, Christian Booz, Simon S. Martin, Doris Leithner, Patricia Tischendorf, Alfredo Blandino, Thomas J. Vogl, Tommaso D'AngeloAbstractPurposeTo define optimal kiloelectron volt (keV) settings for virtual monoenergetic imaging (VMI) reconstruction at dual-energy coronary computed tomography angiography (DE-CCTA).MethodFifty-one DE-CCTA data sets (33 men; mean age, 63.9 ± 13.2 years) were reconstructed as standard linearl...
Source: European Journal of Radiology - Category: Radiology Source Type: research
ConclusionsBoth 18F-HX4 and 18F-FMISO PET/CT can be used as biomarkers for tumor hypoxia and radiotherapy-associated changes. The clinical utilization of these two PET tracers needs to be further validated.
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
THE HIGH COST OF LOW VALUE CARE. Trans Am Clin Climatol Assoc. 2019;130:60-70 Authors: McGinn T, Cohen S, Khan S, Richardson S, Oppenheim M, Wang J Abstract The main focus of this study is bridging the "evidence gap" between frontline decision-making in health care and the actual evidence, with the hope of reducing unnecessary diagnostic testing and treatments. From our work in pulmonary embolism (PE) and over ordering of computed tomography pulmonary angiography, we integrated the highly validated Wells' criteria into the electronic health record at two of our major academic tertiary hospita...
Source: Transactions of the American Clinical and Climatological Association - Category: General Medicine Tags: Trans Am Clin Climatol Assoc Source Type: research
Publication date: Available online 14 September 2019Source: Artificial Intelligence in MedicineAuthor(s): U. Rajendra Acharya, Kristen M. Meiburger, Joel En Wei Koh, Jahmunah Vicnesh, Edward J. Ciaccio, Oh Shu Lih, Sock Keow Tan, Raja Rizal Azman Raja Aman, Filippo Molinari, Kwan Hoong NgAbstractCardiovascular diseases are the primary cause of death globally. These are often associated with atherosclerosis. This inflammation process triggers important variations in the coronary arteries (CA) and can lead to coronary artery disease (CAD). The presence of CA calcification (CAC) has recently been shown to be a strong predicto...
Source: Artificial Intelligence in Medicine - Category: Bioinformatics Source Type: research
In this study, researchers studied 438,952 participants in the UK Biobank, who had a total of 24,980 major coronary events - defined as the first occurrence of non-fatal heart attack, ischaemic stroke, or death due to coronary heart disease. They used an approach called Mendelian randomisation, which uses naturally occurring genetic differences to randomly divide the participants into groups, mimicking the effects of running a clinical trial. People with genes associated with lower blood pressure, lower LDL cholesterol, and a combination of both were put into different groups, and compared against those without thes...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Conclusion: Syndesmotic screw removal and weight bearing may be advantageous to achieve final anatomic reduction of the syndesmosis. Syndesmotic screw removal at appropriate time could not improve foot functional outcomes; however, more studies with the larger sample size are required to confirm the results of the study. PMID: 31516888 [PubMed]
Source: Biomed Res - Category: Research Authors: Tags: Adv Biomed Res Source Type: research
In this study, a series of porous mineralized collagen/PCL scaffolds with different pore features were fabricated via freeze-drying and applied in a Sprague Dawley rat cranial bone calvarial defect model. The pore size for four groups increased from 10–45 μm to 40–130 μm. As scaffold porosity increased, the compressive strength decreased from 2.09 ± 0.12 MPa to 0.51 ± 0.04 MPa. The micro-computed tomography three-dimensional reconstruction images showed that as pore size and porosity increased, the amount of new bone formation had a maximum in group 3 (pore size: 20–100...
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
In this study, we developed a programmed electrospun 3D NF collector. It can precisely control the moving speed of NF collector during electrospinning; thereby fabricating 3D NFs with desired microstructures (pore size, pore volume, and interconnectivity). Four types of polycaprolactone (PCL) 3D NF matrices with different microstructures can be obtained concurrently on the NF collector surface, which are set by different forward moving speed of the NF collector device: NF-zero (no move, as control), NF-low (0.085 mm/min), NF-mid (0.158 mm/min) and NF-high (0.232 mm/min). A linear increase of the NF sheet thickness (f...
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
Publication date: Available online 13 September 2019Source: Journal of ColoproctologyAuthor(s): Jagan Balu, Sankar Subramanian, Suresh P, Shankar Narayanan AP, Amamndeep Sing SandhuAbstractHere we describe an infrequent case of gastrointestinal stromal tumor of the rectum in a 57 year-old man with spindle cell neoplasm probably gastrointestinal stromal tumor and CT scan showed tumor from the anterior rectal wall and offered abdominoperineal resection for the same. The patient was started on imatinib and had a significant reduction in symptoms. The patient was reassessed with the CT scan, which showed a reduction in tumor s...
Source: Journal of Coloproctology - Category: Gastroenterology Source Type: research
In this study, we aimed to identify readily available clinical predictors of overall 30-day and one-year mortality in normotensive cancer patients with PE.Methods and ResultsWe performed a retrospective single-center study that included all normotensive cancer patients with PE diagnosed by multidetector computed tomography (MDCT) during emergency department stay between January 2010 and December 2011. Clinical, MDCT and laboratory variables were collected for all patients. A total of 69 patients were included. All-cause mortality was 28% and 55% at 30 days and one year of follow-up, respectively. Lower mean arterial pressu...
Source: Revista Portuguesa de Cardiologia - Category: Cardiology Source Type: research
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