Influence of single nucleotide polymorphism in IL-27 and IL-33 genes on breast cancer.
Influence of single nucleotide polymorphism in IL-27 and IL-33 genes on breast cancer. Br J Biomed Sci. 2018 Nov 08; Authors: Fathi Maroufi N, Matin M, Ghanbari N, Khorrami A, Amini Z, Haj Azimian S, Isazadeh A, Taefehshokr S, Taefehshokr N, Baradaran B PMID: 30406733 [PubMed - as supplied by publisher]
His research brought an end to radical mastectomy, and he pioneered the design and implementation of large-scale multi-institutional randomized clinical trials.Medscape Medical News
Analyst, 2019, Accepted Manuscript DOI: 10.1039/C9AN01653H, PaperYu Zhou, Huiying Xu, Hua Wang, Bang-Ce Ye Exosomes are membrane-enclosed phospholipid extracellular vesicles with a variety of tumor antigens which can be applied in the diagnosis and treatment of cancer due to the high secretion on the... The content of this RSS Feed (c) The Royal Society of Chemistry
Exosomes derived from human umbilical cord mesenchymal stem cells (HUCMSCs) expressing microRNAs (miRs) have been highlighted as important carriers for gene or drug therapy. Hence, this study aimed to explore the role of exosomal miR-148b-3p from HUCMSCs in breast cancer. Clinical samples subjected to RT-qPCR detection revealed that miR-148b-3p was poorly expressed, while tripartite motif 59 (TRIM59) was highly expressed in breast cancer tissues. Online analyses available at miRanda, TargetScan, and miRbase databases revealed that miR-148b-3p could bind to TRIM59, while dual-luciferase reporter gene assay further verified ...
ConclusionsAge is not the only significant factor affecting pathology results. Risk factors should be determined and imaging findings should be considered as well. Every reduction mammoplasty procedure should be regarded as an opportunity for screening the breast tissue of the candidates.Level of evidence: Level IV, risk/prognostic study.
Publication date: Available online 20 October 2019Source: The LancetAuthor(s): Daniel I Sessler, Lijian Pei, Yuguang Huang, Edith Fleischmann, Peter Marhofer, Andrea Kurz, Douglas B Mayers, Tanja A Meyer-Treschan, Martin Grady, Ern Yu Tan, Sabry Ayad, Edward J Mascha, Donal J Buggy, Gang Tan, Zhiyong Zhang, Helen Keane, Maurice Stokes, Oliver Zotti, Michael Gnant, Silvia Perez-ProttoSummaryBackgroundThree perioperative factors impair host defence against recurrence during cancer surgery: the surgical stress response, use of volatile anaesthetic, and opioids for analgesia. All factors are ameliorated by regional anaesthesia...
ConclusionsWhile patient symptoms are important predictors of patient well-being, subjective appraisals of the stressfulness of symptoms, and of patients ’ self-efficacy in managing symptoms, are also key factors. The findings suggest the utility of a stress process model in understanding well-being in breast cancer patients, and point to the potential value of targeting patient appraisals as well as symptoms to improve psychological well-being and quality of life.
ConclusionsThe study suggests that quality of life and body image are temporarily impaired due to RT. Around one third of patients score their long-term AO as unfavourable. These results should be discussed with the patient and could help in the decision making of the treatment plan and in the clarification of the patient ’s expectations.
Women seek out breast cancer screening at different rates as they grow older...Read more on AuntMinnie.comRelated Reading: DBT finds more cancers of all types than FFDM UCSF launches AI center for medical imaging Women born outside U.S. less likely to undergo mammography Image processing shows potential to reduce MBI dose Patient navigation boosts women's screening compliance
Condition: Breast Cancer Stage IV Intervention: Sponsor: Hellenic Cooperative Oncology Group Active, not recruiting