Human leukocyte antigen DQ2/DQ8 positivity in women with history of stillbirth

ConclusionIn women with history of term stillbirth, a significantly higher prevalence of HLA DQ2/DQ8 haplotypes has been found compared to women with previous uneventful pregnancies. In addition, HLA DQ2/DQ8 positivity was significantly associated with suboptimal fetal growth in intrauterine fetal death cases, as shown by an increased prevalence of SGA babies.

Source: American Journal of Reproductive Immunology - October 25, 2018 Category: Allergy & Immunology Authors: Mauro Cozzolino, Caterina Serena, Antonino Salvatore Calabr ó, Elena Savi, Marianna Pina Rambaldi, Serena Simeone, Serena Ottanelli, Giorgio Mello, Giovanni Rombolá, Gianmarco Troiano, Nicola Nante, Silvia Vannuccini, Federico Mecacci, Feli Tags: ORIGINAL ARTICLE Source Type: research