Omega-3 Polyunsaturated Fatty Acids in Critically Ill Patients with Acute Respiratory Distress Syndrome: A Systematic Review and Meta-analysis

Acute respiratory distress syndrome (ARDS) is characterized by an acute inflammatory response in the lung parenchyma leading to severe hypoxemia. Due to its anti-inflammatory and immunomodulatory properties, omega-3 polyunsaturated fatty acids (n-3 PUFA) have been administered to ARDS patients, mostly by enteral route as immune-enhancing diets (IEDs) with eicosapentaenoic acid (EPA), γ-linolenic acid, and antioxidants. However, clinical benefits of n-3 PUFAs in ARDS patients remain unclear, as clinical trials have found conflicting results.
Source: Nutrition - Category: Nutrition Authors: Source Type: research