LY2109761, Transforming Growth Factor β Receptor Type I and Type II Dual Inhibitor, is a Novel Approach to Suppress Endothelial Mesenchymal Transformation in Human Corneal Endothelial Cells

Conclusion: Inhibition of TGF- β receptor type I and type II by LY2109761 maintained the phenotype of CECs and inhibited the EnMT process. These results indicate the possible continuousin vitro expansion of CECs with normal function.Cell Physiol Biochem 2018;50:963 –972

https://www.karger.com/Article/FullText/494480

Source: Cellular Physiology and Biochemistry - October 24, 2018 Category: Cytology Source Type: research