HIF-2 α promotes conversion to a stem cell phenotype and induces chemoresistance in breast cancer cells by activating Wnt and Notch pathways.

CONCLUSION: In conclusion, HIF-2α promoted stem phenotype conversion and induced resistance to PTX by activating Wnt and Notch pathways.
PMID: 30340507 [PubMed - in process]

Source: Clinical Genitourinary Cancer - October 19, 2018 Category: Cancer & Oncology Authors: Yan Y, Liu F, Han L, Zhao L, Chen J, Olopade OI, He M, Wei M Tags: J Exp Clin Cancer Res Source Type: research