17 β-Estradiol reduces inflammation and modulates antioxidant enzymes in colonic epithelial cells.

Conclusions: Estrogen seems to inhibit inflammation in female human colonic epithelial cell lines, through down-regulation of NF-κB and COX-2 expression and induction of anti-oxidant enzymes such as HO-1 and NQO-1.
PMID: 30336658 [PubMed - as supplied by publisher]

Source: The Korean Journal of Internal Medicine - October 20, 2018 Category: Internal Medicine Authors: Son HJ, Kim N, Song CH, Lee SM, Lee HN, Surh YJ Tags: Korean J Intern Med Source Type: research