Mitochondrial Transplantation Prolongs Cold Ischemia Time in Murine Heart Transplantation

Heart transplantation is the preferred treatment strategy for patients suffering from end stage heart failure. This treatment offers the most beneficial survival outcome and improvement of life quality for heart failure patients and each year the number of transplantations performed increases. However, a growing number of patients requiring heart transplantation are indefinitely waitlisted due to the scarcity of donor hearts.1 The latest available Annual Data Report, by the Organ Procurement and Transplantation Network and Scientific Registry of Transplant Recipients shows that only 50% of the candidates waitlisted throughout the year undergo transplantation, which results in significant mortality of patients awaiting heart transplantation.

Source: The Journal of Heart and Lung Transplantation - September 28, 2018 Category: Transplant Surgery Authors: Kamila Moskowitzova, Borami Shin, Kaifeng Liu, Giovanna Ramirez-Barbieri, Alvise Guariento, David Blitzer, Jerusha K. Thedsanamoorthy, Rouan Yao, Erin R. Snay, James A.H. Inkster, Arzoo Orfany, David Zurakowski, Douglas B. Cowan, Alan B. Packard, Gary A. Source Type: research