Reproducibility of carotid-femoral pulse wave velocity in end-stage renal disease patients: methodological considerations

AbstractBackgroundIn end-stage renal disease (ESRD) patients, increased arterial stiffness detected by carotid-femoral pulse wave velocity (cf-PWV) is associated with fatal cardiovascular events and all-cause mortality. Since cf-PWV is an operator-dependent technique, poor reproducibility may be a source of bias in the estimation of arterial stiffness.ObjectivesWe assessed the week-to-week reproducibility of cf-PWV and radial artery pulse wave analysis in healthy subjects and ESRD patients. We also determined the extent of patient eligibility, enrollment, acceptance, and comfort.MethodsIn a cohort study design, independent tonometric examinations of carotid, femoral, and radial arteries were conducted in 20 healthy subjects and 15 ESRD patients attending chronic hemodialysis treatments according to a randomized sequence by two operators on 2  days scheduled 1-week apart. cf-PWV, augmentation index (AIx@HR75) and central pulse pressure (CPP) were the outcome measures. Patients were tested at mid-week and prior to dialysis treatment. The variability on the distance measured between the suprasternal notch and femoral site using two differ ent methods (standard vs direct) was compared. A post-examination survey assessed acceptance and comfort associated with examinations. Reproducibility was evaluated by intra-class correlations (ICCs).ResultsThe mean age for healthy subjects and ESRD patients was 45  ± 12 and 63 ± 16 years, res...
Source: Canadian Journal of Kidney Health and Disease - Category: Urology & Nephrology Source Type: research

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This study was designed to investigate the biocompatibility of hemodialysis procedures, largely depending on the contact of patient's blood with the dialysis membranes. We addressed the issue by comparing the content of the proteolytic enzymes collagenase and cathepsin B and that of neutrophil myeloperoxidase (MPO) and C-reactive protein (CRP) in the blood before and after a single session treatment and a full course of successive 8-week-long therapies with three types of hemodialysis: low-flux (lfHD), high-flux (hfHD), and post-dilution hemodiafiltration (HDF). The study included 19 patients with chronic nephropathy. We f...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
Publication date: Available online 9 December 2019Source: Carbohydrate PolymersAuthor(s): Yifeng Yang, Ming Gao, Bo Zhou, Peian Cai, Tobias E. Larsson, Jinmin Zhao, Tim Melander BowdenAbstractCarbazate groups were grafted on the commercial cellulose membrane (CM) to specifically scavenge the carbonylated proteins for hemodialysis. It confirmed that carbazate groups were successfully covalently attached on the CMs by XPS and EDS, and the modified CMs still saved their original morphology and crystalline structures by SEM and XRD. Furthermore, the modified CMs presented favorable physicochemical stability at wide pH range fr...
Source: Carbohydrate Polymers - Category: Biomedical Science Source Type: research
Conditions:   End Stage Renal Disease on Dialysis;   Peritoneal Dialysis;   Hemodialysis Intervention:   Other: Dialysis modality Sponsor:   Sun Yat-sen University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
CONCLUSION: This case demonstrates the possibility of arterial compression by an adjacent venous stent graft, especially in a patient with a thin habitus and a brachial-brachial arteriovenous graft. Detailed identification of the outflow vein anatomy before stent implantation is mandatory to avoid such a complication. PMID: 31825299 [PubMed - as supplied by publisher]
Source: The Journal of Vascular Access - Category: Surgery Tags: J Vasc Access Source Type: research
CONCLUSION: Ectopic catheter replacement can improve the primary patency rate and auxiliary primary patency rate of catheters. Ectopic catheter replacement may require sufficient surgical skills with digital subtraction angiography, resulting in a better prognosis. PMID: 31820667 [PubMed - as supplied by publisher]
Source: The Journal of Vascular Access - Category: Surgery Tags: J Vasc Access Source Type: research
THURSDAY, Dec. 12, 2019 -- A proximal radial artery endovascular arteriovenous fistula to allow vascular access in patients who require hemodialysis remains highly functional at two years, according to a study recently published online in the...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
A novel endovascular device is a new alternative to surgery for the creation of an arteriovenous fistula for hemodialysis access in those with kidney disease, and has a high level of patient satisfaction.Medscape Medical News
Source: Medscape Transplantation Headlines - Category: Transplant Surgery Tags: Nephrology News Source Type: news
Publication date: Available online 11 December 2019Source: International Journal of Nursing SciencesAuthor(s): Lei Cui, Weixia Chen, Xingxing Yu, Changping JuAbstractPurposePatients undergoing maintenance hemodialysis (MHD) have a higher prevalence of cognitive impairment and inferior cognitive performance than the general population, and those with cognitive impairment are at higher risk of death than those without cognitive impairment. Having diabetes has been associated with an increased risk of cognitive decline in end-stage kidney disease patients treated with peritoneal dialysis or kidney transplant. However, these f...
Source: International Journal of Nursing Sciences - Category: Nursing Source Type: research
AbstractAimThe present study aimed to determine the relationship between spiritual well ‐being and hope through adherence to diet in haemodialysis patients referred to the dialysis centre.DesignThis research was a cross ‐sectional study of a descriptive‐analytical type conducted on 120 patients undergoing haemodialysis in a haemodialysis centre of a hospital affiliated to Dezful University of Medical Sciences using the census method.MethodThe data were collected using a questionnaire and through the laboratory information included in the patient's records. The data collection tools were a demographic information ques...
Source: Nursing Open - Category: Nursing Authors: Tags: RESEARCH ARTICLE Source Type: research
CONCLUSIONS: In this cohort of Chinese patients with MHD, the patients in the control group whose dietary protein intake was 0.9 g/kg/day and total energy intake was 28 kcal/kg/day, maintained well nutritional status during study period. The KA supplement (0.1 g/kg/day) did not improve the essential amino acid/non-essential amino acid ratio, nor did it change the patients' mineral metabolism, inflammatory parameters, or body compositions. PMID: 31833909 [PubMed - as supplied by publisher]
Source: Chinese Medical Journal - Category: General Medicine Authors: Tags: Chin Med J (Engl) Source Type: research
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