NeoVasc shares jump on 12-week Reducer data

Neovasc (NSDQ:NVCN) today saw shares jump after it released 12-week data from the first patient implanted with its Reducer device designed for treating refractory angina. The Reducer system is designed to alter blood flow in the heart’s circulatory system to increase perfusion of oxygenated blood to ischemic areas of heart muscle, and can be placed in a minimally invasive transvenous procedure, the Vancouver-based company said. The patient, implanted with the device in June as part of a compassionate use case, reported the ability to walk several miles without symptoms after having not been able to walk two blocks before experiencing painful angina prior to the implant. The patient also reported that they rarely experienced chest discomfort, with pain levels of between three and four on a 10 point scale. “The positive 12-week follow-up report provided on our first U.S. patient implanted with a Reducer under compassionate use is in line with the results from our clinical studies and the general European experience, as expressed in other medical publications. We are pleased that this patient was able to benefit from the Reducer therapy and is able to resume a more active and more normal life, with much less pain and discomfort,” prez &CEO Fred Colen said in a press release. Shares in Neovasc rose approximately 18.7% today in response, closing at $2.67. Last month, Neovasc said it plans to launch a 1-for-100 reverse stock split on F...
Source: Mass Device - Category: Medical Devices Authors: Tags: Cardiovascular Neovasc Inc. Source Type: news

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We present the unusual case of a patient who had developed recurrent infection and pain that was associated with its use.
Source: The British Journal of Oral and Maxillofacial Surgery - Category: ENT & OMF Authors: Tags: Short communication Source Type: research
Predischarge cardiac testing (PDT) in low risk patients evaluated for acute coronary syndrome (ACS) in a chest pain unit (CPU) remains a challenge. It is unclear whether PDT varies by sex. We analyzed consecutive low risk women and men evaluated in our CPU over a 2 year period and compared the utilization of PDT (exercise treadmill test [ETT], myocardial stress perfusion scintigraphy [MPS], exercise stress echocardiography, invasive coronary angiography, or no test) and incidence of major adverse cardiac events (MACE) at 30 days and 6 months.
Source: The American Journal of Cardiology - Category: Cardiology Authors: Source Type: research
Rationale: Chronic thromboembolic pulmonary hypertension (CTEPH) is a disease with a poor prognosis, characterized by chronic thromboembolic obstruction of the pulmonary arteries and pulmonary hypertension. Balloon pulmonary angioplasty (BPA) is a newly emergent treatment for CTEPH, which may substitute pulmonary endarterectomy, the standard but more invasive treatment for CTEPH. Here, we report the case of a CTEPH patient who underwent 2 noncardiac surgeries without complications after preoperative intervention of BPA. Patient concerns: A 79-year-old man presented with severe osteoarthritis of bilateral knees, with a...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
AbstractBackgroundVisceral artery aneurysms (VAA) are rare vascular lesions. Clinically silent VAA are increasingly detected by cross-sectional imaging but some lesions are at risk for rupture with severe bleeding. The aim of the present study was to evaluate the trends in the interdisciplinary management at a tertiary center.MethodsPatients who underwent treatment for VAA at University Hospital of Bonn between 2005 and 2018 were enrolled in this retrospective study. Demographic, clinical, VAA-specific data as well as information on therapy, early and long-term outcome were collected and statistically analyzed.ResultsForty...
Source: European Journal of Medical Research - Category: Research Source Type: research
Condition:   Postoperative Pain Intervention:   Other: postoperative pain assessment Sponsor:   Cairo University Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
ConclusionsMinimally invasive surgery for esophageal malignancies offers advantages when performed in an environment with sufficient expertise and caseload. Whether robotic-assisted minimally invasive esophagectomy further improves the results has to be investigated in the future. Intraoperative nerve monitoring and visualization of the graft perfusion with indocyanine green fluorescein should be used where available. Enhanced recovery protocols after surgery have become standard.
Source: Memo - Magazine of European Medical Oncology - Category: Cancer & Oncology Source Type: research
In this study, a microdialysis-ultra-high-performance liquid chromatography-tandem mass spectrometry (MD-LC-MS/MS) method was designed for the simultaneous determination of active constituents in the rubber patch, such as paeonol (Pae), eugenol (Eug), and piperine (Pip). A microdialysis probe was implanted in the subcutaneous tissue of a rat, which is intended to detect the subcutaneous concentrations of target components. Saline containing 30% ethanol acted as perfusion fluid. Analytes in the microdialysate were completely separated over an ACQITY UPLC RBEH C18 column (2.1mm×100mm, 1.7μm). The mobile phase was co...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
Authors: Zheng XZ, Shi YY, Chen KQ, Qiao XL, Wang LY Abstract AIMS: To evaluate the feasibility of assessing regional myocardial perfusion using real-time myocardial contrast echocardiography (MCE) at rest for detecting coronary microcirculation abnormalities in methamphetamine abusers.Material and methods: Twenty-two male methamphetamine abusers (11 without chest pain, 11 with chest pain), free of ascertained coronary artery disease, were enrolled in this study. A control group of 22 age-matched male healthy participants was studied for comparison. Standard 2D, flow and tissue Doppler echo with...
Source: Medical Ultrasonography - Category: Radiology Tags: Med Ultrason Source Type: research
​BY GORDON MURPHY, PA-C, MPHThe patient was blue, her primary care physician noted. Quite literally, in fact.The 38-year-old woman had sought care for a recurrent urinary tract infection, and that's when her primary care physician found her pulse oximetry to be 74%. He was concerned about hypoxia and asked us to evaluate her.The patient reported taking an SSRI for anxiety and having a hormone-eluting IUD. She had previously had a Roux-en-Y gastric bypass. She said she had a headache, but had been instructed not to take NSAIDs. She said she had just finished a course of Cipro for her UTI, but continued to be symptomatic w...
Source: The Case Files - Category: Emergency Medicine Tags: Blog Posts Source Type: research
ConclusionsIncidental findings on inpatient CCTAs performed for chest pain have a significant impact on treatment and imaging during and following hospital admission.
Source: Journal of Nuclear Cardiology - Category: Nuclear Medicine Source Type: research
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