Hyperbaric oxygen treatment resistant carbon monoxide poisoning

In literature, carbon monoxide intoxication (COI) is described by nonspecific symptoms (headache, myalgia, dizziness, weakness, confusion, unconsciousness) like in present patient with unconsciousness [1]. All organs, especially brain and heart, can suffer from COI. On radiological images, hypoxic brain injury can be observed in cerebral cortex and white matter, basal ganglia and especially globus pallidus [2]. In long-term, it can also cause to neuropsychiatric disorders, neurocognitive dysfunctions, and delayed encephalopathy in 0.06 –40% of the survivors.
Source: Journal of Clinical Anesthesia - Category: Anesthesiology Authors: Tags: Correspondence Source Type: research

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Carbon monoxide (CO) poisoning is diagnosed in 1 in 100,000 people per year in the UK, more commonly in winter and in more deprived areas. Toxicity occurs mainly through the formation of carboxyhaemoglobin (COHb), causing ischaemia of vital organs. Features are non-specific and include headache, gastrointestinal upset, dizziness, weakness, convulsions, coma, chest pain and dyspnoea. Neuropsychiatric features can appear up to 40 days after the initial exposure. The diagnosis can be missed unless a history of exposure to sources of CO is elicited or a CO alarm triggered.
Source: Medicine - Category: Internal Medicine Authors: Tags: Poisonous substances Source Type: research
According to the latest numbers, roughly 9 million Americans — 4% of U.S. adults — use prescription sleep aids, or medications that can help with insomnia and other sleep issues. And now, some of the most popular prescription sleep drugs must carry stronger safety warnings. In April, the Food and Drug Administration (FDA) mandated black-box warnings — which the agency uses to “call attention to serious or life-threatening risks” — on three sedative-hypnotic sleep aids: eszopiclone (often sold under the brand name Lunesta), zaleplon (Sonata) and zolpidem (Ambien). Hypnotic drugs, which ar...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Drugs Source Type: news
We report a patient with mild carbon monoxide poisoning who had acute dyspnea as the earliest symptom and was later diagnosed with non-ST elevation myocardial infarction (NSTEMI) and acute left heart failure. Patient concerns: A 73-year-old woman complained of dizziness and fatigue with shortness of breath after carbon monoxide intoxication. Diagnoses: This patient had a clear history of carbon monoxide poisoning, acute respiratory distress, bilateral lung dry and moist rale, chest X-ray showed bilateral pulmonary edema, Electrocardiograph indicated general depression of the ST segment of the leads in the chest, card...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
Abstract Carbon monoxide intoxication occurs usually via inhalation of carbon monoxide that is emitted as a result of a fire, furnace, space heater, generator, motor vehicle. A 37-year-old male patient was admitted to the emergency department at about 5:00 a.m., with complaints of nausea, vomiting and headache. He was accompanied by his wife and children. His venous blood gas measures were: pH was 7.29, partial pressure of carbon dioxide (pCO2) was 42 mmHg, partial pressure of oxygen (pO2) was 28 mmHg, carboxyhemoglobin (COHb) was 12.7% (reference interval: 0.5%-2.5%) and oxygen saturation was 52.4%. Electro-cardi...
Source: Undersea and Hyperbaric Medicine - Category: Sports Medicine Authors: Tags: Undersea Hyperb Med Source Type: research
CONCLUSION: Commonly known sources (fire, charcoal grills) aside, many poisonings by smoking a hookah were observed. This study highlights the importance of considering CO poisoning as a differential diagnosis when encountering patients, especially of younger age, with non-specific neurological symptoms, as well as the importance of early initiation of treatment. A direct correlation between CO-Hb values (whether measured noninvasively or by invasive BGA) and the initial symptoms could not be demonstrated. In total, substantial time expired between the diagnosis and start of treatment of patients transported to a...
Source: Der Anaesthesist - Category: Anesthesiology Authors: Tags: Anaesthesist Source Type: research
​BY GORDON MURPHY, PA-C, MPHThe patient was blue, her primary care physician noted. Quite literally, in fact.The 38-year-old woman had sought care for a recurrent urinary tract infection, and that's when her primary care physician found her pulse oximetry to be 74%. He was concerned about hypoxia and asked us to evaluate her.The patient reported taking an SSRI for anxiety and having a hormone-eluting IUD. She had previously had a Roux-en-Y gastric bypass. She said she had a headache, but had been instructed not to take NSAIDs. She said she had just finished a course of Cipro for her UTI, but continued to be symptomatic w...
Source: The Case Files - Category: Emergency Medicine Tags: Blog Posts Source Type: research
CONCLUSION: High-quality, prospective, randomized trials that would enable a definitive judgment of the efficacy of HBOT are currently lacking. PMID: 30765023 [PubMed - in process]
Source: Deutsches Arzteblatt International - Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research
Conclusions: The meta-analysis indicated that compared with CO poisoning patients treated with NBO, HBO treated patients have a lower incidence of neuropsychological sequelae, including headache, memory impairment, difficulty concentrating, disturbed sleep, and delayed neurological sequelae. Taking into consideration the cost-effectiveness of one session of HBO, one session of HBO treatment could be an economical option for patients with CO poisoning with high severity.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research
Carbon monoxide poisoning is a very common intoxication worldwide. Its clinical manifestations vary from symptoms like mild headache and dizziness to more serious issues including death. Less well known are symptoms that occur with a delay of 2-40 days, su...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
We present a comprehensive review of literature on cardiovascular manifestations of CO poisoning and propose a diagnostic algorithm for managing patients with CO poisoning.
Source: American Journal of Therapeutics - Category: Drugs & Pharmacology Tags: Systematic Review and Clinical Guidelines Source Type: research
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