Anesthetic management of carcinoid heart disease after cardiac surgery. A possible use of veno-arterial extracorporeal membrane oxygenation support
Carcinoid heart disease (CHD) is the cardiac manifestation of a “functioning” neuroendocrine tumour. Patients with CHD undergoing cardiac surgery are at higher risk of developing postoperative haemodynamic instability due to carcinoid crisis and right ventricular (RV) dysfunction. In particular the former is related to the clinical vasomotor manifestations d ue to the release of serotonin, 5-hydroxytryptophan, histamine, bradykinin, tachykinins, kallikrein and prostaglandins [1] secreted by neuroendocrine tumours.
Source: Journal of Clinical Anesthesia - Category: Anesthesiology Authors: Nora Di Tomasso, Francesco Carc ò, Cristina Arangino, Monica De Luca, Tiziana Bove, Alberto Zangrillo, Fabrizio Monaco Tags: Correspondence Source Type: research
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