Bilastine vs. hydroxyzine: occupation of brain histamine H1‐receptors evaluated by positron emission tomography in healthy volunteers
ConclusionsA single oral dose of bilastine 20 mg had minimal H1RO, was not associated with subjective sedation or objective impairment of psychomotor performance and was devoid of treatment‐related sedative AEs, thus satisfying relevant subjective, objective and PET criteria as a non‐sedating antihistamine.
Source: British Journal of Clinical Pharmacology - Category: Drugs & Pharmacology Authors: Magí Farré, Clara Pérez‐Mañá, Esther Papaseit, Esther Menoyo, Marta Pérez, Soraya Martin, Santiago Bullich, Santiago Rojas, José‐Raúl Herance, Carlos Trampal, Luis Labeaga, Román Valiente Tags: Pharmacodynamics Source Type: research
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