The profile of IL-4, IL-5, IL-10 and GATA3 in patients with LRBA deficiency and CVID with no known monogenic disease: Association with disease severity.

CONCLUSIONS: Our findings demonstrated that patients with CVID and LRBA deficiency (even with severe infectious and inflammatory complications) have not imbalance in Th2 response, which is in parallel with lower frequency of allergy and asthma in these patients.
PMID: 30193889 [PubMed - as supplied by publisher]

Source: Allergologia et Immunopathologia - September 4, 2018 Category: Allergy & Immunology Authors: Azizi G, Bagheri Y, Yazdani R, Zaki-Dizaji M, Jamee M, Jadidi-Niaragh F, Kamali AN, Abolhassani H, Aghamohammadi A Tags: Allergol Immunopathol (Madr) Source Type: research