68Ga-PSMA-HBED-CC Uptake in Cervical, Celiac, and Sacral Ganglia as an Important Pitfall in Prostate Cancer PET Imaging

Conclusion: 68Ga-PSMA-ligand uptake in ganglia along the sympathetic trunk as assessed by 68Ga-PSMA-HBED-CC PET represents an important pitfall in prostate cancer PET imaging. The 68Ga-PSMA-ligand uptake is higher in celiac ganglia than cervical or sacral ganglia, and the level of 68Ga-PSMA-ligand uptake seems to be patient-related. For the differentiation between lymph node metastases and sympathetic ganglia, both intensity of 68Ga-PSMA-ligand uptake and exact localization and configuration of the respective lesion should be examined carefully.

Source: Journal of Nuclear Medicine - September 4, 2018 Category: Nuclear Medicine Authors: Rischpler, C., Beck, T. I., Okamoto, S., Schlitter, A. M., Knorr, K., Schwaiger, M., Gschwend, J., Maurer, T., Meyer, P. T., Eiber, M. Tags: Clinical Source Type: research