Analysis of Glycoforms and Amino Acids in Infliximab and a Biosimilar Product using New Method with LC/TOF-MS.

In conclusion, our analytical method can analyze not only amino acids but also carbohydrate chains of therapeutic antibodies, and will provide a useful strategy to evaluate bio-medicines including biosimilar antibodies.
PMID: 30158337 [PubMed - as supplied by publisher]

Source: Biological and Pharmaceutical Bulletin - August 30, 2018 Category: Drugs & Pharmacology Authors: Tsuda M, Otani Y, Yonezawa A, Masui S, Ikemi Y, Denda M, Sato Y, Nakagawa S, Omura T, Imai S, Nakagawa T, Hayakari M, Matsubara K Tags: Biol Pharm Bull Source Type: research