Efficient Gene Transfer to Kidney Mesenchymal Cells Using a Synthetic Adeno-Associated Viral Vector
Conclusions
These studies establish a novel method for inducible knockout of floxed genes in mouse mesangium, pericytes, and perivascular fibroblasts and are the foundation for future gene therapy approaches to treat kidney fibrosis.
Source: Journal of the American Society of Nephrology : JASN - Category: Urology & Nephrology Authors: Ikeda, Y., Sun, Z., Ru, X., Vandenberghe, L. H., Humphreys, B. D. Tags: Basic Research Source Type: research
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