Environmental enrichment reverses increased addiction risk caused by prenatal ethanol exposure

Prenatal ethanol exposure (PE) leads to a variety of physical, cognitive, and behavioral deficits, collectively referred to as fetal alcohol spectrum disorders (FASD). One of the deficits is increased risk of addiction to drugs of abuse (Alati et al., 2006; Barbier et al., 2009). Indeed, our previous work shows that PE leads to enhanced amphetamine conditioned place preference and self-administration in adult rats reared in the standard laboratory environment (Hausknecht et al., 2015; Hausknecht et al., 2017; Wang et al., under review).

Source: Drug and Alcohol Dependence - August 25, 2018 Category: Addiction Authors: Ruixiang Wang, Kathryn A. Hausknecht, Ying-Ling Shen, Samir Haj-Dahmane, Paul Vezina, Roh-Yu Shen Tags: Short communication Source Type: research