Aspirin plus clopidogrel may reduce the risk of early neurologic deterioration in ischemic stroke patients carrying CYP2C19 * 2 reduced-function alleles

ConclusionsDual therapy with clopidogrel and aspirin may be adequate for prevention of END in carriers ofCYP2C19 reduced-function alleles, but not for noncarriers. Our findings may be useful to guide precise antiplatelet therapy, and decrease the risk of END.

http://link.springer.com/10.1007/s00415-018-8998-1

Source: Journal of Neurology - August 20, 2018 Category: Neurology Source Type: research