Recombination of a dual-CAR-modified T lymphocyte to accurately eliminate pancreatic malignancy

The therapeutic application of T cells endowing with chimeric antigen receptors (CARs) is faced with “on-target, off-tumor” toxicity against solid tumors, particularly in the treatment of the pancreatic cancer...

Source: Journal of Hematology and Oncology - August 13, 2018 Category: Hematology Authors: Erhao Zhang, Peiwei Yang, Jieyi Gu, Heming Wu, Xiaowei Chi, Chen Liu, Ying Wang, Jianpeng Xue, Weiyan Qi, Qingbo Sun, Shengnan Zhang, Jialiang Hu and Hanmei Xu Tags: Research Source Type: research