K284-6111 prevents the amyloid beta-induced neuroinflammation and impairment of recognition memory through inhibition of NF- κB-mediated CHI3L1 expression

Alzheimer ’s disease, which is pathologically characterized by an excessive accumulation of amyloid beta (Aβ) fibrils, is a degenerative brain disease and the most common cause of dementia. In a previous study,...

Source: Journal of Neuroinflammation - August 11, 2018 Category: Neurology Authors: Ji Yeon Choi, In Jun Yeo, Ki Cheon Kim, Won Rack Choi, Jae-Kyung Jung, Sang-Bae Han and Jin Tae Hong Tags: Research Source Type: research