Intracranial Response to Anti-Programmed Death 1 Therapy in a Patient with Metastatic Non-Small Cell Lung Cancer with Leptomeningeal Carcinomatosis.

Intracranial Response to Anti-Programmed Death 1 Therapy in a Patient with Metastatic Non-Small Cell Lung Cancer with Leptomeningeal Carcinomatosis.
Oncologist. 2018 Aug 02;:
Authors: Kamath SD, Kumthekar PU, Kruser TJ, Mohindra NA
Abstract
Central nervous system metastasis in non-small cell lung cancer remains a therapeutic challenge and confers a poor prognosis. Here we describe a patient with lung adenocarcinoma, parenchymal brain metastases, and leptomeningeal carcinomatosis who demonstrated a sustained response to programmed death 1 inhibition combined with stereotactic radiosurgery.
PMID: 30072392 [PubMed - as supplied by publisher]

Source: The Oncologist - August 2, 2018 Category: Cancer & Oncology Authors: Kamath SD, Kumthekar PU, Kruser TJ, Mohindra NA Tags: Oncologist Source Type: research