18F-PBR111 PET Imaging in Healthy Controls and Schizophrenia: Test-Retest Reproducibility and Quantification of Neuroinflammation

Conclusion: 18F-PBR111 can be used for monitoring of TSPO binding, as shown by medium test–retest variability and reliability of VT in HCs. Microglial activation is present in SPs depending on age and needs to be adjusted for genotype.

Source: Journal of Nuclear Medicine - August 2, 2018 Category: Nuclear Medicine Authors: Ottoy, J., De Picker, L., Verhaeghe, J., Deleye, S., wyffels, L., Kosten, L., Sabbe, B., Coppens, V., Timmers, M., van Nueten, L., Ceyssens, S., Stroobants, S., Morrens, M., Staelens, S. Tags: Clinical Source Type: research