What you see and what you don & #39;t - Utility and pitfalls during fluorescence guided resections of gliomas using 5-aminolevulinic acid

Conclusions: ALA guided resections are very useful in malignant gliomas, even if these lesions do not enhance signi cantly. Although ALA reliably depicts the tumour intraoperatively, it may not be possible to resect all this tissue completely. Additionally, non-fluorescing tumor may be completely missed out and may require additional imaging tools. Working within the limitations of the technique and using complementary modalities (ultrasound or brain mapping) may be ideal for achieving a radical resection of malignant gliomas.

Source: Neurology India - July 18, 2018 Category: Neurology Authors: Aliasgar V Moiyadi Epari Sridhar Prakash Shetty Venkatesh S Madhugiri Sohan Solanki Source Type: research