GFAP{alpha} IgG-associated encephalitis upon daclizumab treatment of MS

Conclusions Our case of GFAPα IgG-associated encephalitis along with 12 other cases of serious inflammatory brain disorders following daclizumab treatment so far indicates that interfering with NK cells and Tregs by anti-CD25 antibody therapy can result in severe secondary CNS autoimmunity in man.

http://nn.neurology.org/cgi/content/short/5/5/e481?rss=1

Source: Neurology Neuroimmunology and Neuroinflammation - July 13, 2018 Category: Neurology Authors: Luessi, F., Engel, S., Spreer, A., Bittner, S., Zipp, F. Tags: Autoimmune diseases, Multiple sclerosis Article Source Type: research