Enhanced transdermal delivery of meloxicam by nanocrystals: Preparation, in vitro and in vivo evaluation

In conclusion, nanocrystal is advantageous for transdermal delivery of MLX.Graphical AbstractMeloxicam nanocrystals were successfully prepared by the nanoprecipitation technique based on acid-base neutralization. Nanocrystals significantly increased both in vitro and in vivo transdermal permeation of meloxicam due to increased transdermal concentration gradient and facilitated follicular permeation.
Source: Asian Journal of Pharmaceutical Sciences - Category: Drugs & Pharmacology Source Type: research