What are the effects of the guidelines-recommended treatments of myocardial infarction on the secretion of pro- and anti-inflammatory cytokins in an in vitro murin inflammatory model?

ConclusionAspirin, abciximab and unfractionned heparin have an important anti-IL-1β effect, reducing its secretion. This could explain the lack of efficacy of the specific anti-IL-1β treatments during the acute phase of myocardial infarction. These results should be confirmed using an in vivo murin model and a human in vitro model.
Source: Archives of Cardiovascular Diseases Supplements - Category: Cardiology Source Type: research