Urinary mitochondrial DNA level in non-diabetic chronic kidney diseases

ConclusionMitochondrial DNA is readily detectable in the urinary supernatant of non-diabetic CKD, and its level correlates with the rate of renal function decline and predicts the risk of doubling of serum creatinine or need of dialysis. Further studies are needed to determine the value of urinary supernatant mtDNA level as a prognostic indicator of non-diabetic CKD
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research