Sensorineural Deafness Following Tacrolimus Use.

Sensorineural Deafness Following Tacrolimus Use.
Exp Clin Transplant. 2018 Jul 02;:
Authors: Lakshmi BS, Vidya B, Reddy MHK, Kumar ACV, Ram R, Kumar VS
Abstract
Early trials of tacrolimus in renal transplant recipients have not revealed hearing loss as an adverse effect. Here, we present a case report and a review of the literature of deafness after tacrolimus use. The review of the literature and our experience suggested that the possible reason for hearing loss could be due to an initiation of a sudden spike in the tacrolimus serum level, which was later worsened by its cumulative toxic effect.
PMID: 29969081 [PubMed - as supplied by publisher]

Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - July 2, 2018 Category: Transplant Surgery Authors: Lakshmi BS, Vidya B, Reddy MHK, Kumar ACV, Ram R, Kumar VS Tags: Exp Clin Transplant Source Type: research