Functional magnetic resonance imaging with encoding task in patients with mild cognitive impairment and different severity of leukoaraiosis

Dementia is one of the most relevant causes of disability in the elderly as it affects 5.4% of people over 65 years and its prevalence increases with age. Alzheimer's disease (AD) represents the main type of dementia, however vascular dementia (VaD) is also frequently encountered (Di  Carlo et al., 2002). VaD is often caused by small vessel disease (SVD) whose pathological hallmarks are represented by leukoaraiosis (also called age related changes in white matter), lacunar infarcts, microbleeds and parenchymal haemorrhage (Pantoni, 2010).

Source: Psychiatry Research: Neuroimaging - July 2, 2018 Category: Psychiatry Authors: Alberto Chiti, Paolo Cecchi, Ilaria Pesaresi, Giovanni Orlandi, Nicola Giannini, Gino Gialdini, Eva Terni, Gloria Tognoni, Leda Volpi, Cristina Pagni, Irene Ghicopulos, Gabriele Siciliano, Maria Teresa Dotti, Antonio Federico, Anna Poggesi, Emilia Salvado Source Type: research